tag:blogger.com,1999:blog-1881251140360229837.comments2023-07-11T21:16:12.345+01:00Mourne Training ServicesUnknownnoreply@blogger.comBlogger16125tag:blogger.com,1999:blog-1881251140360229837.post-17527780034904251112018-05-01T06:50:35.049+01:002018-05-01T06:50:35.049+01:00Thank you very much for posting this, Oona! Thank you very much for posting this, Oona! Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-50069184380799099782015-07-01T17:47:19.230+01:002015-07-01T17:47:19.230+01:00Found this blog very for my BTECFound this blog very for my BTECAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-38686969430345990372015-03-08T07:49:06.839+00:002015-03-08T07:49:06.839+00:00Your blog provided us with valuable information to...Your blog provided us with valuable information to work with. Thanks a lot for sharing. Keep blogging. <br /><a href="http://www.clickperfect.co.in/courses/google-analytics-training" rel="nofollow">Analytics Training</a><br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-33866101803903671712013-09-06T13:42:49.609+01:002013-09-06T13:42:49.609+01:00The article is based on practice in the UK but I d...The article is based on practice in the UK but I don't see why it would be any different in the US. The steps are flexible and should be used in the way that is most appropriate for your training requirements.Oona McPolinhttps://www.blogger.com/profile/11016193415167924469noreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-24999493072543241052013-05-07T09:15:04.744+01:002013-05-07T09:15:04.744+01:00hi, is this the American training cycle or the UK ...hi, is this the American training cycle or the UK training cycle??Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-42156444347805834672013-03-15T10:13:34.636+00:002013-03-15T10:13:34.636+00:00A delay of 60% is quite large, I think that the mo...A delay of 60% is quite large, I think that the most likely cause is related to an increase in the organic content of the mobile phase composition. Although you believe that there has been no change to the conditions, I would check this thoroughly.<br /><br />It is unlikely that the change would be due to the pump if the flow rate and pressure are satisfactory but it could be due to a problem with the mobile phase mixer.Oona McPolinhttps://www.blogger.com/profile/11016193415167924469noreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-2686061285528267462013-03-14T18:23:27.548+00:002013-03-14T18:23:27.548+00:00I'm having this problem, since about a month a...I'm having this problem, since about a month ago, and all peaks are very consistently delayed ~60%, with no apparent change to the method, solvents, columns, compounds, etc.<br /><br />I've changed columns to no effect. I assume that this has something to do with the pumps, but the pressure is constant and at the same level as before the shift, as well as the external flow rate. I'm not quite sure where to go from here, but I'll try to flush any air from the lines which may be causing the delay.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-85464582804961408252012-11-04T10:29:41.926+00:002012-11-04T10:29:41.926+00:00Dear Miss Oona McPolin,
I appreciate very much you...Dear Miss Oona McPolin,<br />I appreciate very much your answers to the questions, they help me very much! Thanks in advance,<br /><br />Sincerely Yours <br />Fatos Osmani<br />Senior HPLC Analyst<br />Profarma sh.a.<br />Tirane AlbaniaAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-40791534491018212032011-10-02T14:09:10.054+01:002011-10-02T14:09:10.054+01:00So for gradient is measurement at half height appr...So for gradient is measurement at half height appropriate?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-79949093322536049462011-08-12T07:54:28.022+01:002011-08-12T07:54:28.022+01:00This approach is also useful for labs without open...This approach is also useful for labs without open access instruments. We got our engineers following similar protocols to those described in this article and it's cutting the time it takes to perform the sample preparation by at least half. Also, we are not so much interested in the absolute assay but instead relative concentrations of solutions so we know, for example when we have reached saturation point. This is a neat approach.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-46506985456215718122011-07-27T10:39:42.002+01:002011-07-27T10:39:42.002+01:00Reduction of method factors by combining them (whi...Reduction of method factors by combining them (which the authors advocate) is an interesting approach which will certainly help reduce resource. Care must be taken however not to 'group' together factors that may have opposite effects on a given response as this would result in factor effects being masked. To be fair the authors point out "Scientific judgement, therefore, must be used when allocating combinations to ensure that the effects of the parameters do not cancel each other out....", ..."As a rule, parameters can be combined if they have the same direction of effect (e.g., if increasing the pH and the % organic will increase the resolution) or if they affect different method performance characteristics."<br /><br />Out of interest the same authors have just written a paper on "Method ruggedness studies incorporating a risk based approach: A tutorial" in Analytica Chimica Acta. This is how I found this blogAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-15712879878485745462011-04-16T01:00:11.482+01:002011-04-16T01:00:11.482+01:00Thanks. this is a very informative post. I hope to...Thanks. this is a very informative post. I hope to see more updates online because I learn a lot. The blog is really informative and I get to share this information to my students. Nice design too.. very simple but elegant. <br /><a href="http://www.training.com.br/" rel="nofollow">curso sap</a>Unknownhttps://www.blogger.com/profile/04389920492975074164noreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-46559179126255864332011-01-12T12:25:39.887+00:002011-01-12T12:25:39.887+00:00Part II was planned but for some reason I never go...Part II was planned but for some reason I never got round to posting it. Hopefully should be available soon!Oona McPolinhttps://www.blogger.com/profile/11016193415167924469noreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-244932600034877302011-01-12T11:29:20.858+00:002011-01-12T11:29:20.858+00:00Hi, Oona!
Is there a Part II post? I can´t find i...Hi, Oona!<br /><br />Is there a Part II post? I can´t find it...<br /><br />Thanks,<br /><br />PatríciaPatrícia Gonçalvesnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-44566713156730854992010-04-23T14:05:22.308+01:002010-04-23T14:05:22.308+01:00You're right Oona, input from method/technique...You're right Oona, input from method/technique experts and stats experts is vital to the success of any method risk assessment/study of this nature.<br /><br />In order to maximise the method understanding we can generate compared to the resource we put in we must move away from the old:<br />-statisician receives a work package<br />-supplies an experimental regime<br />-receives experimental data<br />-provides a report.<br />To a much more inclusive one team approach with everyone providing their own insight to make the studies work as slickly as possible.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1881251140360229837.post-44005456176523936162009-09-24T15:12:59.981+01:002009-09-24T15:12:59.981+01:00Wow! I love this. Having all this information in o...Wow! I love this. Having all this information in one location is a great help.<br /><br />Thank You!Pete Scottnoreply@blogger.com